Campbell is a music marketing director and has owned her own music publishing company since 1995. She served as mayor of Oak Hill, a small suburb south of Nashville from 2014 to 2020.
In the 2020 elections, she won the Democratic primary for a seat in the Tennessee Senate before defeating two-term Republican incumbent Steven Dickerson, 51.7% to 48.3%.
In April 2022, Campbell announced her candidacy for Tennessee's 5th congressional district in the United States House of Representatives after incumbent Jim Cooper chose to retire. The district encompasses Nashville-Davidson County and five other Tennessee counties. Although the 5th district had been traditionally Democratic, it was redrawn in the redistricting cycle to favor Republicans, and Republican Andy Ogles defeated Campbell.